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Classification of Skeletal Muscle Fibers

Classification of Skeletal Muscle Fibers

Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...

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Updated: Jun 18, 2025

$X-ray Diffraction of Intact Murine Skeletal Muscle as a Tool for Studying the Structural Basis of Muscle Disease$

X-ray Diffraction of Intact Murine Skeletal Muscle as a Tool for Studying the Structural Basis of Muscle Disease

Published on: July 18, 2019

MuscleX: data analysis software for fiber diffraction patterns from muscle.

Jiranun Jiratrakanvong¹, Jinjian Shao², Jiaqi Li²

¹BioCAT, CSRRI and Department of Biology, Illinois Institute of Technology, Chicago, IL 60616, USA.

Journal of Synchrotron Radiation

|July 30, 2024

Summary

This summary is machine-generated.

MuscleX is a new open-source software suite designed for X-ray fiber diffraction data analysis. This powerful tool simplifies data reduction for muscle and fibrous systems, offering both graphical and command-line interfaces.

Keywords:

MuscleX data reduction fiber diffraction fibrous systems graphical user interfaces muscles

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$X-ray Diffraction of Intact Murine Skeletal Muscle as a Tool for Studying the Structural Basis of Muscle Disease$

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Semi-automated Analysis of Mouse Skeletal Muscle Morphology and Fiber-type Composition

Semi-automated Analysis of Mouse Skeletal Muscle Morphology and Fiber-type Composition

Published on: August 31, 2017

Area of Science:

Biophysics
Structural Biology
Computational Science

Background:

X-ray fiber diffraction is crucial for studying the structure of fibrous biological systems.
Analyzing diffraction patterns requires specialized software for accurate data reduction.
Existing tools may lack integration, flexibility, or ease of use for complex datasets.

Purpose of the Study:

To introduce MuscleX, an integrated, open-source software suite for X-ray fiber diffraction data.
To provide a comprehensive overview of MuscleX's modular structure and functionalities.
To demonstrate the application of MuscleX in analyzing diffraction data from muscle and other fibrous systems.

Main Methods:

Development of MuscleX using Python for cross-platform compatibility (Linux, Windows, macOS).
Implementation of a graphical user interface (GUI) for interactive use.
Inclusion of a command-line 'headless mode' for automated data processing and integration into beamline control systems.

Main Results:

MuscleX offers a unified platform for X-ray fiber diffraction data reduction.
The software supports diverse fibrous systems, including striated muscle.
Both GUI and headless modes are available, enhancing usability and automation capabilities.

Conclusions:

MuscleX provides a versatile and accessible solution for processing X-ray fiber diffraction data.
Its open-source nature and flexible interface facilitate wider adoption in structural biology research.
The software is well-suited for both routine analysis and integration into advanced experimental setups.