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Updated: Jun 27, 2026
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Choroidal Vascularity Index and Subfoveal Choroidal Thickness in Rheumatoid Arthritis Assessed with Enhanced-Depth
Mustafa Berhuni1, Fatih Albayrak2, Mehmet Göl3
1Department of Ophthalmology, Ersin Arslan Training and Research Hospital, Gaziantep, Turkey.
Purpose:
To evaluate the effects of rheumatoid arthritis (RA) on choroidal vascularity index (CVI) and subfoveal choroidal thickness (SFCT).
Methods:
The study included 56 eyes of 56 rheumatoid arthritis patients and 65 eyes of 65 age- and sex-matched healthy normal participants. CVIs of all participants were measured by transferring enhanced depth imaging optical coherence tomography (EDI-OCT) images to the image J program that is software used for image binarization and compared between the 2 groups. SFCT, central macular thickness (CMT) and optic disc parameters of all participants were measured with spectral domain OCT and compared.
Results:
The mean CVI values of the RA and control groups were 65.9 ± 1.52 and 68.56 ± 1.62, respectively, and were significantly lower in the RA group (p = 0.001). Mean SFCT values of the RA and control groups were 290.11 ± 15.18 and 332.88 ± 11.04, respectively, and SFCT was significantly lower in the RA group (p = 0.001). RA patients have thin SFCT and low CVI. There was no significant difference between the two groups in terms of CMT and optic disc parameters.
Conclusion:
RA patients have lower CVI and thinner SFCT than healthy participants.
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