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Updated: Jun 18, 2025
Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Identification of a new flavonol glucuronide from Alpinia oxyphylla
Jiao Zhao1, Dawei Ji2, Qiang Chen3
1Department of Gynecology, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University, Cancer Hospital of Dalian University of Technology, Shenyang, China.
Abstract:
The fruits of Alpinia oxyphylla has been used a famous traditional Chinese medicine. A chemical investigation on the fruits of A. oxyphylla resulted in the isolation of one new acetylated flavanol glucuronide (1) and two known compounds (2-3). Compound 1 displayed a weak inhibitory effect on U251 cells with the IC50 value 128.51 μM while the positive control drug temozolomide exhibited the IC50 value 35.37 μM.
