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Updated: Jun 18, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

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Mild Cognitive Impairment and Suicidal Ideation Among Adults Aged 65 Years or Older From Low- and Middle-Income

Lee Smith1, Guillermo Felipe López Sánchez2, Pinar Soysal3

  • 1Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.

The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
|July 30, 2024
PubMed
Abstract

Insights

Mild cognitive impairment (MCI) significantly increases suicidal ideation odds in older adults from low- and middle-income countries. This highlights MCI as a critical indicator for suicide risk assessment in global aging populations.

Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • Mild cognitive impairment (MCI) is a recognized indicator of distress.
  • MCI's association with suicide risk requires further investigation, particularly in diverse global settings.
  • No prior studies have explored the link between MCI and suicidal ideation.

Purpose of the Study:

  • To investigate the association between MCI and suicidal ideation.
  • Focus on adults aged 65 and older.
  • Study conducted in six low- and middle-income countries (LMICs).

Main Methods:

  • Utilized cross-sectional, nationally representative data from the WHO's Study on Global Ageing and Adult Health.
  • Defined MCI using National Institute on Aging-Alzheimer's Association criteria.
  • Analyzed self-reported past 12-month suicidal ideation using multivariable logistic regression and meta-analysis.

Main Results:

  • Analyzed data from 13,623 individuals aged ≥65 years.
  • Prevalence of suicidal ideation varied from 0.5% (China) to 6.0% (India).
  • MCI was associated with 1.66 times higher odds of suicidal ideation (95% CI: 1.12-2.46) after adjusting for confounders.

Conclusions:

  • MCI is significantly linked to increased odds of suicidal ideation in older adults within LMICs.
  • MCI may serve as a crucial warning sign for suicide risk in this demographic.
  • Further longitudinal research in LMICs is recommended to confirm MCI as a risk factor.
Keywords:
Cognitive declinePublic healthSuicidal thoughtsSuicide risk

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