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Updated: Jun 18, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
COVID-19 hospitalisations in a tertiary health service during the Omicron subvariant wave
Alysha Y Wanigaratne1, Mohana Baptista2, Freya Langham3
1Monash University School of Clinical Sciences at Monash Health, Monash Medical Centre, Clayton, VIC 3168, Australia.
Objectives:
COVID-19 Omicron subvariants typically cause milder disease than previous strains, yet many patients were still admitted to hospital for acute care. We audited reasons for and details of admissions to identify opportunities to reduce hospitalisations.
Methods:
We reviewed all admitted patients who tested positive for SARS-CoV-2 from 1st December 2022 to 30th January 2023.
Results:
Of 600 patients with a positive COVID-19 polymerase chain reaction, 222(37%) were considered incidental diagnoses. Reasons for admission for symptomatic COVID-19 (375 patients, 63%) included worsening symptoms (226, 60%), exacerbation of comorbidities (89, 24%), and difficulty managing at home (38, 10%). Almost half were classified as a mild infection (175, 47%). Of the 231 patients aged over 70 years, only 55 (24%) had prior antiviral therapy, and 90 (39%) had 4+ vaccine doses. Patients speaking language other than English and having country of birth other than Australia were significantly associated with lower vaccination rates and not having antivirals prior to admission.
Conclusions:
One-third of COVID-19 hospital admissions were incidental, and half were for mild disease. Many patients had not received appropriate vaccination or antivirals in the community.
Implications For Public Health:
Improving uptake of vaccinations and antivirals, and increasing community support, with a focus on people from culturally and linguistically diverse backgrounds, may reduce the burden of COVID-19 on hospitals.
Insights
Many hospital admissions for COVID-19 were for mild illness or incidental cases. Improving vaccination and antiviral uptake, especially in diverse communities, could reduce hospitalizations.
Area of Science:
- Public Health
- Infectious Diseases
- Health Services Research
Background:
- COVID-19 Omicron subvariants generally cause less severe illness.
- Despite milder disease, hospital admissions for acute care remain a concern.
- Understanding admission drivers is key to reducing healthcare burdens.
Purpose of the Study:
- To audit reasons for and details of hospital admissions for SARS-CoV-2.
- To identify opportunities for reducing COVID-19 hospitalizations.
Main Methods:
- Retrospective review of all admitted patients testing positive for SARS-CoV-2.
- Data collected from December 1st, 2022, to January 30th, 2023.
Main Results:
- 37% of 600 positive cases were incidental diagnoses.
- Symptomatic COVID-19 admissions (63%) were due to worsening symptoms (60%), comorbidity exacerbation (24%), or home management difficulties (10%).
- 47% of symptomatic cases had mild infections; many elderly patients lacked prior antiviral therapy (76%) or adequate vaccination (61%).
- Lower vaccination and antiviral rates were observed in non-English speaking patients and those born outside Australia.
Conclusions:
- One-third of COVID-19 admissions were incidental; half were for mild disease.
- Inadequate community vaccination and antiviral use were prevalent.
- Targeted interventions for vaccination, antivirals, and community support, particularly for culturally and linguistically diverse populations, are recommended to decrease hospital admissions.
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