Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Introduction to Fibroblasts

Introduction to Fibroblasts

Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, such as growth factors and inflammatory cytokines. Activated fibroblasts play a crucial role in wound healing, inflammation, formation of new blood vessels, and cancer progression. Uncontrolled activation of fibroblasts results in fibrosis, the excess deposition of fibrous tissue, which can lead to scarring and affect normal organs. This...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Is the presence of a first rib fracture in patients with polytrauma an indicator of severe trauma? A retrospective study on associated injuries and clinical outcomes.

Pakistan journal of medical sciences·2026

Same author

The effects of the Buzzy device on pain, anxiety, blood pressure, and pulse rate during venous blood sampling in adults: a randomised controlled study.

Irish journal of medical science·2025

Same author

Anterior mediastinal hematoma caused by internal mammary artery injury following sternal fracture after blunt trauma: A case report.

Irish journal of medical science·2025

Same author

The Reliability of the Evaluation of Diffusion-Weighted Imaging in Suspected Stroke by Emergency Physicians.

Journal of neurosciences in rural practice·2020

Same author

One-stage combined thoracic ancient schwannomas total removal and coronary artery bypass.

Case reports in medicine·2011

Same author

Cavernous hemangioma of the rib: a case report.

Asian cardiovascular & thoracic annals·2008

Search research articles

Related Experiment Video

Updated: Jun 18, 2025

Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata

Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata

Published on: November 23, 2017

Elastofibroma Dorsi: experience of a single center.

Kadri Ceberut¹, Burak Hasgül²

¹Department of Thoracic Surgery.

Cirugia Y Cirujanos

|July 30, 2024

Summary

Elastofibroma dorsi (ED), a rare back tumor, requires attention. Surgical management in 20 patients showed no recurrences, indicating a safe and effective treatment approach for this benign condition.

Keywords:

Clinical presentation Diagnosis Diagnóstico Elastofibroma dorsi Follow-up Presentación clínica Seguimiento Tratamiento Treatment

More Related Videos

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions

Published on: April 18, 2015

Murine Dermal Fibroblast Isolation by FACS

Murine Dermal Fibroblast Isolation by FACS

Published on: January 7, 2016

Related Experiment Videos

Last Updated: Jun 18, 2025

Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata

Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata

Published on: November 23, 2017

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions

Published on: April 18, 2015

Murine Dermal Fibroblast Isolation by FACS

Murine Dermal Fibroblast Isolation by FACS

Published on: January 7, 2016

Area of Science:

Oncology
Surgical Pathology

Background:

Elastofibroma dorsi (ED) is a rare, benign tumor typically found in the subscapular area.
Clinical presentation often includes swelling in the back region.

Purpose of the Study:

To evaluate clinical findings, surgical approach, and management of ED.
To analyze single-center data and relevant literature for ED treatment.

Main Methods:

Retrospective evaluation of 20 patients operated on for ED.
Standard surgical procedures were employed for all cases.

Main Results:

The study included 16 females (80%) and 4 males (20%).
Swelling was the primary complaint in 80% of patients; 50% had unilateral involvement.
No recurrences were observed during a mean follow-up of 26.6 months (range 6-53 months).
Post-operative complications included seroma (10%) and infection (5%), both managed conservatively.

Conclusions:

ED, though rare, should be considered in patients presenting with back swelling.
Clinical and radiological diagnosis is crucial before surgical intervention.
Surgery for ED is a safe and effective treatment option with no observed recurrences.