Prostate stromal sarcoma mimicking benign prostate hyperplasia: A case report
Fauriski Febrian Prapiska1, Rizky An Nabil2, Syah Mirsya Warli3
1Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara - Haji Adam Malik General Hospital, Medan, Indonesia.
Prostate stromal sarcoma is a rare cancer often misdiagnosed as benign prostate hyperplasia. Early suspicion and histopathology are crucial for accurate diagnosis and better patient outcomes.
Area of Science:
- Oncology
- Urology
Background:
- Prostate stromal sarcoma is an extremely rare malignancy, representing less than 1% of prostate cancers.
- It is often misdiagnosed due to presenting symptoms similar to other lower urinary tract symptoms (LUTS).
Observation:
- A 45-year-old male presented with obstructive LUTS, anorexia, and weight loss.
- Initial diagnosis was benign prostate hyperplasia (BPH), treated with transurethral resection of the prostate (TURP), but symptoms recurred and worsened.
Findings:
- Histopathological examination confirmed prostate stromal sarcoma (T4N0M0).
- Magnetic Resonance Imaging (MRI) was used for further evaluation.
- Radical prostatectomy was performed.
Implications:
- High clinical suspicion is necessary for patients with recurrent LUTS, as prostate stromal sarcoma can mimic BPH or other prostate cancers.
- Accurate and timely diagnosis, primarily through histopathology, is essential for improving patient prognosis.
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