Related Experiment Video
Updated: Aug 8, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Autologous Pericranium Graft for Necrotizing Scleritis
Sergio Copete1, María Antonia Fagúndez-Vargas1, Franciso López-Martínez1
1Ophthalmology Department, Albacete University Hospital Complex, Albacete, Spain; and.
Purpose:
The purpose of this study was to describe the clinical outcome of scleral staphyloma secondary to necrotizing scleritis treated with autologous pericranial grafting.
Case Report:
A 63-year-old woman with necrotizing scleritis and choroidal protrusion underwent homologous scleral grafting, which failed. The patient's medical management was optimized for control of her systemic inflammation, and she underwent a second surgery consisting of autologous pericranium grafted to the parietal region. A 3- × 2-cm tissue patch was harvested and sutured over the staphyloma borders with 8/0 polyglactin sutures. Complete re-epithelialization was observed at 3 weeks, the graft was well integrated, and no signs of inflammation were observed at 18 months.
Conclusions:
The pericranium offers a viable alternative for scleral thinning because of necrotizing scleritis.

