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Updated: Jun 18, 2025

Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease
Published on: April 17, 2017
Enhancing respiratory function in neuromuscular disease: the role of non-invasive ventilation. A narrative review
Paolo Banfi1, Agata Alba Maria Domenica Buscemi2,3, Elena Compalati1
1IRCCS Fondazione Don Carlo Gnocchi - ONLUS, Milan, Italy.
Abstract:
Neuromuscular diseases (NMDs) comprise a heterogeneous group of conditions characterized by extreme progressive muscle weakness leading to respiratory failure. Noninvasive mechanical ventilation (NIV) has emerged as a cornerstone in the management of respiratory complications associated with NMDs. This review aims to elucidate the role of NMV in respiratory function, improving quality of life, and prolonging survival in individuals with NMD. The physiological basis of respiratory impairment in NMDs, principles of NMV application, evidence supporting its efficacy, patient selection criteria, and potential challenges in its application are discussed.
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