Related Experiment Video
Updated: Jun 18, 2025
04:44
Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
234
Sexual function in patients with bipolar disorder type I evaluated in symptomatic remission: a cross-sectional study
Juliana Socorro Casqueiro1, Vitor Fernandes de Almeida2, Gabriela Léda-Rêgo3
1rograma de Pós-Graduação em Medicina e Saúde Pública, Universidade Federal da Bahia (UFBA), Salvador, BA, Brazil. Centro de Estudos dos Transtornos de Humor e de Ansiedade (CETHA), UFBA, Salvador, BA, Brazil. Departamento de Neurociências e Saúde Mental, Faculdade de Medicina, UFBA, Salvador, BA, Brazil. Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil.
Trends in Psychiatry and Psychotherapy
|July 31, 2024
Summary
Bipolar disorder (BD) patients experience significantly higher rates of sexual dysfunction (SD) compared to healthy individuals. This sexual dysfunction is linked to poorer quality of life (QoL) in BD patients.
Area of Science:
- Psychiatry
- Sexual Medicine
- Quality of Life Research
Background:
- Bipolar disorder (BD) is a chronic mental health condition impacting various life aspects.
- Sexual function is crucial for quality of life (QoL) but remains understudied in BD patients.
- Decreased sexual function is a common impairment in individuals with BD.
Purpose of the Study:
- To compare sexual function in euthymic Bipolar Disorder type I (BD-I) patients versus healthy controls (HC).
- To identify clinical and socio-demographic factors associated with sexual dysfunction (SD) in BD-I patients.
- To evaluate the impact of SD on QoL among BD-I patients.
Main Methods:
- A cross-sectional study involving 132 BD-I patients and 61 HCs.
- Participants completed the Arizona Sexual Scale (ASEX) and WHOQoL-BREF.
- BD-I patients were compared to HCs, and grouped by presence or absence of SD.
Main Results:
- BD-I patients exhibited a higher prevalence of SD (42.4%) than HCs (16.4%).
- SD in BD-I was associated with female gender, older age, and longer duration of untreated illness.
- Patients with SD reported significantly worse QoL scores across all domains.
Conclusions:
- There is a high prevalence of sexual dysfunction in Bipolar Disorder type I patients.
- Sexual dysfunction is significantly associated with diminished quality of life in BD-I.
- Addressing sexual dysfunction is crucial for improving overall well-being in BD patients.
Related Concept Videos
01:30Bipolar Disorder
61
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
61
01:24Mania and Antimanic Drugs: Overview
157
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
157
01:26Psychosis: Goals of Pharmacotherapy
114
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
114
01:25Borderline Personality Disorder
38
Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
Genetic and Environmental Contributions
Borderline Personality...
38
01:23Antidepressant Drugs: MAOIs and Other Agents
209
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
209
01:28Psychosis and Antipsychotic Drugs: Overview
214
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
214