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Cardiac Arrest Due to Capecitabine Toxicosis Treated With ECMO and CRRT: A Case Report
Liqin Zhang1, Mingjun Liu2, Lutao Xie3
1Liqin Zhang is a resident physician in the Department of Intensive Care Medicine, Lishui Municipal Central Hospital, Lishui City, Zhejiang Province, China.
Introduction:
This is the first report of a patient who developed cardiogenic shock after receiving oral chemotherapy with capecitabine and was treated with venoarterial extracorporeal membrane oxygenation combined with continuous renal replacement therapy.
Clinical Findings:
A 58-year-old man developed an arrhythmia that rapidly progressed to cardiogenic shock and cardiac arrest after receiving oral capecitabine tablets to treat a rectal malignancy.
Interventions:
The patient was treated with venoarterial extracorporeal membrane oxygenation in combination with continuous renal replacement therapy.
Outcome:
The patient made a full recovery and was discharged from the hospital.
Conclusion:
The use of comprehensive supportive treatments such as extracorporeal membrane oxygenation combined with continuous renal replacement therapy in patients with capecitabine-induced cardiac arrest can rapidly reduce drug concentrations, eliminate harmful substances, and improve the prognosis.
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