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Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
Published on: August 4, 2018
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Development of a Low-Cost Scanning Laser Ophthalmoscope Using Semiconductor Laser Technology
Hiroki Takizawa1, Hiroshi Kunikata1,2, Takeshi Yabana1
1Department of Ophthalmology, Tohoku University Graduate School of Medicine.
The Tohoku Journal of Experimental Medicine
|July 31, 2024
Summary
A new, low-cost scanning laser ophthalmoscopy (SLO) device was developed for accessible eye diagnostics. This safe, non-invasive technology provides clear imaging of ocular diseases without pupil dilation.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Scanning laser ophthalmoscopy (SLO) is crucial for ophthalmic diagnostics but limited by high costs.
- Existing SLO devices often require pupil dilation and focus adjustment, hindering accessibility.
Purpose of the Study:
- To develop and evaluate a low-cost, safe, and user-friendly SLO prototype.
- To assess the efficacy of the prototype in imaging ocular pathologies without pupil dilation or focus adjustment.
Main Methods:
- Development of a prototype SLO utilizing semiconductor laser technology with red (638 nm) and infrared (IR; 795 nm) lasers.
- Examination of 53 patients (93 eyes) with glaucoma, branch retinal vein occlusion (BRVO), and diabetic retinopathy (DR).
Main Results:
- Successful high-quality imaging was achieved in 83 eyes (47 patients).
- The non-invasive device clearly visualized the optic nerve head (ONH) and retinal vessels.
- Ophthalmological findings including ONH cupping, macular edema, and retinal hemorrhage were detectable.
Conclusions:
- The developed low-cost SLO effectively captures ocular morphology and pathology.
- This technology offers potential for enhanced accessibility in ophthalmic diagnostics, especially in resource-limited settings.
- It can aid in the early detection and management of various eye diseases.

