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Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
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Primary hepatic diffuse large B- cell lymphoma mimicking cholangiocarcinoma
Taruna Yadav1, Deepanksha Datta2,3, Poonam Elhence4
1Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, India.
EJNMMI Reports
|July 31, 2024
Summary
Primary liver lymphoma, a rare cancer, presents with vague symptoms, making early diagnosis challenging. This case highlights imaging techniques like CT, MRI, and PET/CT for identifying this malignancy.
Area of Science:
- Hepatology
- Oncology
- Radiology
Background:
- Primary liver lymphoma is an exceptionally rare hepatic malignancy.
- Clinical and laboratory features are often non-specific, mimicking other liver diseases.
- Distinguishing it from other hepatic lesions can be diagnostically challenging.
Purpose of the Study:
- To present a case of Primary Diffuse Large B-cell Lymphoma of the liver.
- To illustrate the characteristic imaging findings of this rare condition across multiple modalities.
- To emphasize the importance of integrating imaging with pathological diagnosis for timely treatment.
Main Methods:
- Case report of a patient diagnosed with Primary Diffuse Large B-cell Lymphoma of the liver.
- Review of imaging studies including Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (F-18 FDG PET/CT).
Main Results:
- The study details the specific appearances of primary liver lymphoma on CT, MRI, and F-18 FDG PET/CT.
- Imaging findings, while variable, can suggest the diagnosis when correlated with clinical context.
- Pathological confirmation remains the definitive diagnostic method.
Conclusions:
- Primary liver lymphoma requires a high index of suspicion due to its rarity and non-specific presentation.
- Multimodality imaging plays a crucial role in characterizing hepatic lesions and guiding diagnosis.
- Early and accurate diagnosis is vital for appropriate management and improved patient outcomes.

