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Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
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Associations between dietary total antioxidant capacity and sarcopenia: a cross-sectional study
Azadeh Aminianfar1,2, Rezvan Hashemi3, Fatemeh Emami4,5
1Students' scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Nutrition Journal
|July 31, 2024
Summary
Higher dietary total antioxidant capacity (d-TAC) is linked to lower odds of sarcopenia in older adults. This study found an inverse relationship, suggesting antioxidants may play a role in preventing age-related muscle loss.
Area of Science:
- Gerontology
- Nutritional Science
- Geriatric Medicine
Background:
- Sarcopenia is a significant health concern in aging populations.
- The role of dietary total antioxidant capacity (d-TAC) in sarcopenia remains unexplored.
Purpose of the Study:
- To investigate the association between d-TAC and sarcopenia in elderly adults.
- To determine if dietary antioxidant intake influences the risk of developing sarcopenia.
Main Methods:
- Cross-sectional study of 300 elderly adults (≥55 years).
- Sarcopenia assessed using EWGSOP criteria, DXA, dynamometry, and gait speed.
- Dietary intake evaluated via a food frequency questionnaire (FFQ).
Main Results:
- Individuals in the highest d-TAC tertile exhibited greater hand grip strength.
- Higher d-TAC was associated with significantly lower odds of sarcopenia (OR=0.33; 95% CI: 0.11, 0.95) after confounder adjustment.
- No significant association found between d-TAC and individual sarcopenia components.
Conclusions:
- An inverse association exists between dietary total antioxidant capacity and the odds of sarcopenia.
- d-TAC may be a protective factor against sarcopenia in the elderly.
- Further research is warranted to confirm these findings and explore mechanisms.

