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Updated: Jun 18, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Treatment outcomes in non-occlusive mesenteric ischemia and post-treatment return to social activities
Gaku Ohira1, Koichi Hayano2, Toru Tochigi2
1Department of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan. Ohira@faculty.chiba-u.jp.
Purpose:
To investigate the treatment outcomes of patients with non-occlusive mesenteric ischemia (NOMI) at our institution, we focused on their post-treatment return to social activities.
Methods:
This study included patients with suspected NOMI who were referred to our department between 2011 and 2023. In-hospital mortality was also investigated as a prognostic factor. The Glasgow-Pittsburgh Outcome Categories (GPOC) score was used to evaluate the return to social activities. The relationship between in-hospital mortality and GPOC scores and patient background and treatment factors was examined.
Results:
Eighty-two patients were included in the study. Among them, 54 (65.9%) died during hospitalization. Only 9 patients (11%) returned to their social activities. In the multivariate analysis, non-surgical management was found to be the only independent factor for in-hospital mortality. Positive portal venous gas on computed tomography, no open abdomen, no pre-onset catecholamine administration, platelet count < 100,000/µL, lactate level < 5 mmol/L, APTT < 46 s, and Sequential Organ Failure Assessment score < 11 were factors significantly associated with an increased likelihood of return to social activities.
Conclusion:
This is the first study to assess the post-treatment return to social activities among patients with NOMI. Our findings highlight the concerning reality that survivors may face prolonged dependence on medical care.

