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Updated: Aug 8, 2026

Development of an Insert Co-culture System of Two Cellular Types in the Absence of Cell-Cell Contact
11:29

Development of an Insert Co-culture System of Two Cellular Types in the Absence of Cell-Cell Contact

Published on: July 17, 2016

The increase in immunosuppression and its role in the development of malignant lesions

W H Cole

    Journal of Surgical Oncology
    |November 1, 1985
    PubMed

    The first evidence that a major operation results in immunosuppression appeared in 1957. A few years later, numerous articles appeared in the medical literature showing that the same effect took place in the human being. When kidney transplantation was begun, it was soon learned that immunosuppression was necessary to obtain good results. Soon after suppression was adopted it was noted that malignancies were being encountered. The same was true with cardiac transplantation. Within the many types of immunodeficiencies, malignant lesions are significantly encountered in only one--AIDS.

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