Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Convolution: Math, Graphics, and Discrete Signals01:24

Convolution: Math, Graphics, and Discrete Signals

240
In any LTI (Linear Time-Invariant) system, the convolution of two signals is denoted using a convolution operator, assuming all initial conditions are zero. The convolution integral can be divided into two parts: the zero-input or natural response and the zero-state or forced response, with t0 indicating the initial time.
To simplify the convolution integral, it is assumed that both the input signal and impulse response are zero for negative time values. The graphical convolution process...
240
Neural Circuits01:25

Neural Circuits

1.1K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.1K
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

3.2K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
3.2K
Convolution Properties II01:17

Convolution Properties II

179
The important convolution properties include width, area, differentiation, and integration properties.
The width property indicates that if the durations of input signals are T1 and T2, then the width of the output response equals the sum of both durations, irrespective of the shapes of the two functions. For instance, convolving two rectangular pulses with durations of 2 seconds and 1 second results in a function with a width of 3 seconds.
The area property asserts that the area under the...
179
Action Potential: Phases of Stimulation01:28

Action Potential: Phases of Stimulation

5.3K
The action potential is a complex electrical event that occurs in excitable cells, such as neurons and muscle cells. It consists of several distinct phases, each with specific characteristics.
Resting Phase:
In this phase, the cell's membrane is at its resting potential, typically around -70 millivolts (mV) for neurons. Inside the cell, there is a higher concentration of potassium ions (K+) and a lower concentration of sodium ions (Na+). Voltage-gated sodium channels are closed, and...
5.3K
Motor Unit Stimulation01:20

Motor Unit Stimulation

1.5K
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Induction of significant neutralizing antibodies against SARS-CoV-2 by a highly attenuated pangolin coronavirus variant with a 104nt deletion at the 3'-UTR.

Emerging microbes & infections·2022
Same author

Hydrothermal synthesis of sewage sludge biochar for activation of persulfate for antibiotic removal: Efficiency, stability and mechanism.

Environmental research·2022
Same author

Effects of Biofilms on Trace Metal Adsorption on Plastics in Freshwater Systems.

International journal of environmental research and public health·2022
Same author

Destabilization of the Charge Density Wave and the Absence of Superconductivity in ScV<sub>6</sub>Sn<sub>6</sub> under High Pressures up to 11 GPa.

Materials (Basel, Switzerland)·2022
Same author

Foliar Application of Reaction Products Derived from Selenite Removal by Iron Monosulfide for <i>Brassica rapa</i> ssp. <i>Chinensis</i> L.

Environmental science & technology·2022
Same author

Pembrolizumab for treatment of a male with primary mediastinal choriocarcinoma: a case report.

Translational cancer research·2022
Same journal

Hidden Data Recovery and Forecasting via Next-Generation Reservoir Computing With Multiscale Delay Selection.

IEEE transactions on neural networks and learning systems·2026
Same journal

CAFF-CIL: Causality-Aware Freedom Forgetting Approach for Class-Incremental Learning.

IEEE transactions on neural networks and learning systems·2026
Same journal

Harmonic Autoencoding Framework for Multiple Tasks in Magnetic Particle Imaging Reconstruction.

IEEE transactions on neural networks and learning systems·2026
Same journal

A Survey on Human-Centric Voice-Face Multimodal Learning.

IEEE transactions on neural networks and learning systems·2026
Same journal

Vision-Assisted Foundation Model for Solving Multitask Vehicle Routing Problems.

IEEE transactions on neural networks and learning systems·2026
Same journal

FP3O: Enabling Proximal Policy Optimization in Multiagent Cooperation With Parameter-Sharing Versatility.

IEEE transactions on neural networks and learning systems·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2025

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
08:32

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

Published on: May 7, 2017

13.3K

Understanding Convolutional Neural Networks From Excitations.

Zijian Ying, Qianmu Li, Zhichao Lian

    IEEE Transactions on Neural Networks and Learning Systems
    |August 1, 2024
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces Positive and Negative Excitation (PANE) to explain convolutional neural network (CNN) decisions without gradients. PANE improves saliency maps by utilizing all layer information, outperforming existing methods.

    More Related Videos

    Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
    11:18

    Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

    Published on: March 2, 2015

    10.3K
    Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
    08:08

    Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

    Published on: June 24, 2015

    11.5K

    Related Experiment Videos

    Last Updated: Jun 18, 2025

    External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
    08:32

    External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures

    Published on: May 7, 2017

    13.3K
    Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
    11:18

    Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

    Published on: March 2, 2015

    10.3K
    Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
    08:08

    Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

    Published on: June 24, 2015

    11.5K

    Area of Science:

    • Artificial Intelligence
    • Computer Vision
    • Machine Learning

    Background:

    • Saliency maps explain Convolutional Neural Network (CNN) decisions.
    • Current methods use gradients, limiting complex model explanations and negative gradient use.
    • This restricts interpretive veracity and full layer information utilization.

    Purpose of the Study:

    • Introduce a novel method, Positive and Negative Excitation (PANE), for CNN interpretability.
    • Enable direct, gradient-free extraction of PANE for each layer.
    • Improve saliency map generation by leveraging complete layer information.

    Main Methods:

    • Directly extract Positive and Negative Excitation (PANE) for each layer, bypassing gradient reliance.
    • Introduce a double-chain backpropagation procedure to organize excitations into saliency maps.
    • Conduct comprehensive experiments on binary and multiclassification tasks.

    Main Results:

    • The proposed PANE method significantly improves salient and minor pixel removal.
    • PANE offers superior guidance for generating inconspicuous adversarial perturbations.
    • Experimental results demonstrate the effectiveness of layer-by-layer PANE extraction and correlation verification.

    Conclusions:

    • PANE provides a gradient-free approach for enhanced CNN interpretability.
    • The method achieves state-of-the-art performance in improving saliency map quality.
    • PANE offers a more comprehensive understanding of CNN decision-making processes.