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What Is the Best Technique for Treating Carotid Disease?
Ahmed Abdelkarim1, Mohammed Hamouda1, Mahmoud B Malas1
1Department of Surgery, Division of Vascular and Endovascular Surgery, UC San Diego, San Diego, CA, USA; Center for Learning and Excellence in Vascular & Endovascular Research (CLEVER), UC San Diego, San Diego, CA, USA; Altman Center for Clinical and Translational Research, 9452 Medical Center Drive - LL2W 502A, La Jolla, CA 92037, USA.
Transcarotid Artery Revascularization (TCAR) offers a safer alternative for high-risk patients needing carotid artery revascularization, showing results comparable to Carotid Endarterectomy (CEA) and better outcomes than Transfemoral Carotid Artery Stenting (TFCAS).
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Carotid artery disease poses a significant stroke risk.
- Surgical and endovascular techniques aim to restore blood flow.
- Choosing the optimal revascularization strategy is critical for patient outcomes.
Purpose of the Study:
- To comprehensively review and compare Carotid Endarterectomy (CEA), Transfemoral Carotid Artery Stenting (TFCAS), and Transcarotid Artery Revascularization (TCAR).
- To evaluate the safety and efficacy of each technique, particularly in high-risk patient populations.
- To inform clinical decision-making for carotid artery revascularization.
Main Methods:
- Systematic review of existing literature on CEA, TFCAS, and TCAR.
- Comparative analysis of procedural outcomes, including stroke rates, mortality, and neuroprotection.
- Assessment of patient-specific factors influencing technique selection.
Main Results:
- Carotid Endarterectomy (CEA) remains a gold standard, especially for elderly and high-risk individuals.
- Transfemoral Carotid Artery Stenting (TFCAS) is less invasive but associated with higher periprocedural stroke risks.
- Transcarotid Artery Revascularization (TCAR) combines minimally invasive advantages with neuroprotection, demonstrating comparable efficacy to CEA and superior outcomes to TFCAS in high-risk patients.
Conclusions:
- TCAR represents a promising and safer option for high-risk patients undergoing carotid revascularization.
- Patient comorbidities and anatomical considerations are crucial in selecting the most appropriate revascularization strategy.
- Further research may refine optimal patient selection criteria for each technique.
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