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Related Experiment Video

Updated: Jun 18, 2025

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
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Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

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Advances in single-cell transcriptomics in animal research.

Yunan Yan1, Senlin Zhu1, Minghui Jia1

  • 1Institute of Dairy Science, Ministry of Education Key Laboratory of Molecular Animal Nutrition, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.

Journal of Animal Science and Biotechnology
|August 1, 2024
PubMed
Summary

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Single-cell transcriptomics revolutionizes animal research by revealing cellular details for improved health and production. This technology offers insights into gene expression, cell interactions, and developmental paths in livestock.

Area of Science:

  • Animal Genomics
  • Molecular Biology
  • Biotechnology

Background:

  • Understanding animal biology is crucial for enhancing livestock production and health.
  • Single-cell transcriptomics is an emerging technology for analyzing gene expression in individual animal cells.
  • This technique provides high-throughput data from diverse tissues and organs.

Purpose of the Study:

  • To review the development, processes, advancements, and applications of single-cell transcriptomics in animal research.
  • To summarize recent findings in animal nutrition, health, reproduction, genetics, and disease models using this technology.
  • To provide practical insights for key analytical factors and discuss future directions.

Main Methods:

  • Review of single-cell transcriptomics technologies and their application in animal studies.
Keywords:
Disease modellingGeneticsHealthLivestockNutritionReproductive performanceSingle-cell RNA sequencing

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Related Experiment Videos

Last Updated: Jun 18, 2025

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
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Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

18.5K
Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells
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Published on: January 7, 2020

12.9K
Transcriptome Analysis of Single Cells
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Transcriptome Analysis of Single Cells

Published on: April 25, 2011

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  • Analysis of gene expression patterns in individual cells from various animal tissues.
  • Identification of cell types, marker genes, cellular trajectories, and cell-cell interactions.

    • Main Results:

    • Single-cell transcriptomics enables unprecedented identification of cell types, marker genes, and cellular fate.
    • The technology has advanced understanding in animal nutrition, health, reproduction, genetics, and disease models.
    • Key analytical factors like sample size and cell annotation are critical for successful studies.

    Conclusions:

    • Single-cell transcriptomics offers profound insights into animal biology, driving advancements in agricultural productivity and animal health.
    • The technology is a powerful tool for dissecting complex biological mechanisms in livestock.
    • Continued development and application hold significant promise for sustainable animal agriculture.