Multidisciplinary management of type 2 inflammation diseases using a screening tool

Area of Science:

• Immunology
• Allergy
• Pulmonology
• Dermatology
• Otorhinolaryngology

Background:

• Dysregulation of the type 2 (T2) immune response underlies various organ-specific inflammatory diseases.
• Coexisting T2-related disorders are common but often overlooked due to fragmented care and diagnostic challenges.
• Mild T2 dysregulation may not be initially suspected, leading to delayed diagnosis and suboptimal patient management.

Purpose of the Study:

• To identify cardinal symptoms of common T2 inflammation-related diseases.
• To develop a simple, patient-friendly screening tool for coexisting T2 diseases.
• To facilitate early detection and appropriate specialist referral for patients with T2 dysregulation.

Main Methods:

• A multidisciplinary expert group compiled a list of key symptoms from patients with T2 inflammation-related conditions.
• The identified symptoms were used to create a questionnaire for initial patient screening.
• The proposed questionnaire is designed for administration at any healthcare level.

Main Results:

• A comprehensive list of cardinal symptoms associated with T2 inflammation-related diseases was established.
• A patient-friendly questionnaire was developed based on these symptoms.
• The questionnaire aims to facilitate the identification of patients with potential coexisting T2 diseases.

Conclusions:

• Early screening for T2 inflammation-related diseases is crucial for timely diagnosis and management.
• The developed questionnaire offers a practical tool for identifying patients who may benefit from specialist evaluation.
• Improved interdisciplinary communication and screening tools can enhance care coordination for patients with T2 dysregulation.