Recent racial/ethnic disparities in cancer-specific mortality among patients diagnosed with rectal cancer
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View abstract on PubMed
Summary
This summary is machine-generated.Racial disparities in rectal cancer mortality persist, particularly for Black patients, even after accounting for clinical factors and treatment. Addressing healthcare inequities is crucial to reduce these survival outcome gaps.
Area Of Science
- Oncology
- Health Services Research
- Health Disparities
Background
- African American patients often receive suboptimal rectal cancer treatment, leading to poorer survival outcomes compared to White patients.
- Racial and ethnic disparities in rectal cancer mortality are a significant public health concern.
- Understanding the factors contributing to these disparities is essential for improving patient care.
Purpose Of The Study
- To analyze racial and ethnic disparities in rectal cancer-specific mortality.
- To determine if these disparities persist after adjusting for clinical characteristics, treatment, and access-to-care factors.
Main Methods
- Utilized the Surveillance, Epidemiology, and End Results Database for individuals diagnosed with rectal cancer between 2011 and 2020.
- Calculated cumulative incidence of rectal cancer-specific mortality.
- Employed Fine and Gray regression models to estimate sub-distribution hazard ratios (sdHRs) with stepwise adjustments.
Main Results
- Non-Hispanic Black patients had the highest cumulative incidence of rectal cancer-specific mortality (39%).
- NH-Black patients showed a 28% increased risk of mortality compared to NH-White patients, even after clinical adjustments.
- Disparities for Hispanic, American Indian/Alaska Native, and Asian/Pacific Islander groups were not significant after adjustments.
Conclusions
- Racial/ethnic disparities in rectal cancer mortality are significantly influenced by differences in clinical characteristics, treatment, and access to care.
- The observed Black-White mortality gap in rectal cancer persists after accounting for these factors.
- Equitable healthcare is essential to mitigate racial/ethnic disparities in rectal cancer outcomes.
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