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Published on: October 16, 2021
Mitral Valve Repair in a 15-Month-Old Child With Kingella kingae Endocarditis
Matthew D McGee1, Sunni A Coyne1, Renish N Contractor2
1Pediatrics, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Insights
Kingella kingae endocarditis is rare but serious in children. Early diagnosis via blood cultures and imaging is crucial for prompt treatment and preventing complications.
Area of Science:
- Infectious Diseases
- Pediatric Cardiology
- Microbiology
Background:
- Kingella kingae is a HACEK organism commonly found in the oropharynx.
- While rare, Kingella kingae can cause infective endocarditis, particularly in young children.
- This case highlights a previously healthy 15-month-old male with Kingella kingae endocarditis.
Observation:
- The patient initially presented with symptoms mimicking an upper respiratory infection.
- Blood cultures, drawn at 60 hours, confirmed the presence of Kingella kingae.
- Echocardiogram and brain MRI revealed mitral valve vegetation and septic emboli.
Findings:
- Kingella kingae endocarditis can present insidiously with non-specific respiratory symptoms.
- Delayed blood culture identification is possible, necessitating a high index of suspicion.
- Multiorgan involvement, including cerebral septic emboli, can occur.
Implications:
- Prompt diagnosis and treatment of Kingella kingae endocarditis are vital for favorable outcomes in pediatric patients.
- Noninvasive imaging like ultrasound may aid in ruling out atypical pathologies in children with respiratory symptoms.
- This case underscores the importance of considering rare bacterial causes of endocarditis in pediatric febrile illnesses.
Abstract:
Kingella kingae, a Haemophilus parainfluenzae, Aggregatibacter actinomycetemcomitans, Aggregatibacter aphrophilus, Cardiobacterium hominis, Eikenella corrodens, K. kingae (HACEK) organism, is commonly found in the oropharynx. Although it rarely causes endocarditis, it can pose a significant risk to young children. We report a case of K. kingae endocarditis in a previously healthy 15-month-old male who initially presented with symptoms of an upper respiratory infection. Blood cultures taken at 60 hours revealed the presence of K. kingae. Subsequent echocardiogram and brain MRI demonstrated large vegetation on the mitral valve and septic emboli in the right occipital and left posterior parietal lobes. The patient was treated with intravenous ceftriaxone and underwent mitral valve repair with annuloplasty. This case illustrates the presentation of K. kingae endocarditis with initial respiratory symptoms and the subsequent identification of the infection through blood cultures and imaging. For pediatric patients presenting with upper respiratory symptoms, there may be clinical benefit to noninvasive ultrasound imaging to help rule out atypical pathologies like endocarditis.
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