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Updated: Jun 18, 2025

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
Published on: September 20, 2018
A case report of interstitial pneumonia induced by vedolizumab in a patient with ulcerative colitis
Ailing Liu1, Susu Ye2, Zeyuan Diao1
1Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China.
Rationale:
The interstitial pneumonia (IP) linked to vedolizumab (VDZ) in patients with ulcerative colitis (UC) is rare. Prompt diagnosis and treatment can improve patient outcomes.
Patient Concerns:
A 39-year-old man with UC who received VDZ as sole therapy developed symptoms such as chest tightness, cough, and suffocation.
Diagnoses:
IP was confirmed through pulmonary function tests, chest computed tomography, and bronchoscopic biopsy.
Interventions:
The patient was given methylprednisolone and VDZ cessation.
Outcomes:
The patient's symptoms improved and remained symptom-free after nearly 2 years.
Lessons:
VDZ-induced IP should be considered when evaluating pulmonary infections in UC patients treated with VDZ.
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