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Updated: May 5, 2026

Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging
Published on: April 6, 2014
SECONDARY MULTIPLE EVANESCENT WHITE DOT SYNDROME AFTER BLUNT TRAUMA
Samantha R Goldburg1,2, Jennifer Adeghate3, Gaetano R Barile1,2,4
1Department of Ophthalmology, Northwell, New Hyde Park, New York.
Background/Purpose:
To report a case of secondary unilateral multiple evanescent white dot syndrome after blunt trauma to the eye.
Methods:
Observational case report of one patient.
Results:
A 25-year-old man initially presented after being hit in the left eye with a football, with visual acuity of 20/50, traumatic iritis, commotio retinae, vitreous hemorrhage, and a large pigment epithelial detachment in the superior macula. He was lost to follow-up for 2 years before presenting with a sudden decrease in vision. On examination, best-corrected visual acuity was counting fingers, and clinical examination demonstrated fibrosis in the superior macula, small white lesions around the optic disk and throughout the posterior pole and ellipsoid zone disruption on optical coherence tomography. Given the clinical appearance, a diagnosis of multiple evanescent white dot syndrome was made and the decision was made to observe. Two months later, without treatment, best-corrected visual acuity improved to 20/20, and there was resolution of the white lesions in the posterior pole as well as improved continuity of the ellipsoid zone on optical coherence tomography.
Conclusion:
The authors describe a case of multiple evanescent white dot syndrome 2 years after blunt trauma to the eye; a far longer latency than previously reported cases of multiple evanescent white dot syndrome secondary to blunt trauma.
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