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Enhanced ICL Sizing Accuracy Using Advanced Optical Coherence Tomography-Based Predictive Formula.

Kazuya Yamashita1, Manabu Kobayashi1, Akihito Igarashi1

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A new formula using ANTERION device measurements improves implantable collamer lens (ICL) sizing accuracy. This method enhances prediction of postoperative vault outcomes, outperforming existing NK and KS formulas for better ICL selection.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Accurate implantable collamer lens (ICL) sizing is crucial for predictable refractive outcomes and minimizing complications.
  • Existing ICL sizing formulas, such as NK and KS, have limitations in predicting postoperative vault.
  • Advanced imaging devices like CASIA2 and ANTERION offer precise preoperative measurements.

Purpose of the Study:

  • To evaluate the accuracy of current NK and KS ICL sizing formulas using CASIA2 and ANTERION devices.
  • To develop and introduce a novel, more accurate formula for predicting ICL size and postoperative vault.
  • To improve the predictability of refractive outcomes following ICL implantation.

Main Methods:

  • Retrospective analysis of preoperative measurements from CASIA2 and ANTERION devices.
  • Comparison of predicted vault heights from NK and KS formulas against actual postoperative measurements.
  • Stepwise multiple regression analysis to identify key parameters for a new predictive ICL sizing formula.

Main Results:

  • The novel formula derived from ANTERION measurements showed superior accuracy in predicting ICL size and vault (0.535 ± 0.200 mm).
  • Existing NK and KS formulas yielded less accurate vault predictions (0.419 ± 0.172 mm and 0.466 ± 0.103 mm, respectively).
  • Multiple regression analysis identified significant predictors for optimal ICL sizing.

Conclusions:

  • A new ICL sizing formula utilizing ANTERION device data significantly improves prediction accuracy.
  • This novel approach enhances the predictability of postoperative vault, potentially reducing ICL-related complications.
  • The study highlights the utility of advanced biometric devices and regression analysis for optimizing ICL selection.