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Updated: May 8, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Visualising myocardial injury after noncardiac surgery: a case series using postoperative cardiovascular MRI
Dominik P Guensch1, Jan O Friess2, Sandra Stiffler2
1Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department of Diagnostic, Interventional and Paediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Abstract:
Myocardial injury after noncardiac surgery (MINS) and perioperative myocardial injury are associated with increased morbidity and mortality. Both are diagnosed by a perioperative increase in troponin, yet there is controversy if MINS is a genuine myocardial insult. We applied postoperative cardiovascular magnetic resonance T2 mapping techniques to visualise acute myocardial injury (i.e. oedema) in six patients with multiple cardiovascular risk factors who underwent aortic surgery. The burden of myocardial oedema was substantially higher in four patients with elevated troponin qualifying for MINS, compared with patients without MINS. The data and images suggest that MINS represents genuine myocardial injury.
Insights
Myocardial injury after noncardiac surgery (MINS) is a genuine cardiac event, not just a troponin rise. Cardiovascular magnetic resonance imaging shows significant myocardial edema in patients with MINS, confirming acute injury.
Area of Science:
- Cardiology
- Medical Imaging
- Cardiovascular Surgery
Background:
- Myocardial injury after noncardiac surgery (MINS) and perioperative myocardial injury are linked to higher morbidity and mortality.
- Diagnosis relies on troponin increase, but the nature of MINS as a true myocardial insult remains debated.
Observation:
- Postoperative cardiovascular magnetic resonance T2 mapping was used to visualize acute myocardial injury (edema).
- Six patients with cardiovascular risk factors undergoing aortic surgery were studied.
Findings:
- Patients qualifying for MINS exhibited a substantially higher burden of myocardial edema compared to those without MINS.
- The imaging data provides visual evidence supporting MINS as a genuine myocardial injury.
Implications:
- These findings suggest MINS is a true myocardial insult, not merely a biomarker elevation.
- Understanding MINS as genuine injury could refine perioperative cardiac risk assessment and management strategies.
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