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Updated: Jun 18, 2025

Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells
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Delivery vehicle and route of administration influences self-amplifying RNA biodistribution, expression kinetics, and

Nuthan Vikas Bathula1, Josh J Friesen1, Irafasha C Casmil2

  • 1Michael Smith Laboratories, University of British Columbia, Vancouver V6T 1Z4, Canada; School of Biomedical Engineering, University of British Columbia, Vancouver V6T 1Z3, Canada.

Journal of Controlled Release : Official Journal of the Controlled Release Society
|August 3, 2024
PubMed

Keywords:
BiodistributionGene therapyInflammationRNA therapeuticsReactogenicityRoute of administrationSelf Amplifying RNA

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