Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vesicular Tubular Clusters01:45

Vesicular Tubular Clusters

2.5K
After budding out from the ER membrane, some COPII vesicles lose their coat and fuse with one another to form larger vesicles and interconnected tubules called vesicular tubular clusters or VTCs. These clusters constitute a compartment at the ER-Golgi interface known as ERGIC (Endoplasmic Reticulum Golgi Intermediate Compartment). The ERGIC is a mobile membrane-bound cargo transport system that sorts proteins secreted from ER and delivers them to the Golgi.
With the help of motor proteins such...
2.5K
Renal Tubule and Collecting Duct01:24

Renal Tubule and Collecting Duct

880
The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
880
Pleiotropy01:33

Pleiotropy

40.3K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
40.3K
Histology of the Small Intestine01:27

Histology of the Small Intestine

617
The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
617
Renewal of Intestinal Stem Cells01:23

Renewal of Intestinal Stem Cells

2.5K
The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
2.5K
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

100
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
100

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Derivatization of (±) dihydrotetrabenazine for copper-64 labeling towards long-lived radiotracers for PET imaging of the vesicular monoamine transporter 2.

Bioorganic & medicinal chemistry letters·2014
Same author

Coordination mode of pentadentate ligand derivative of 5-amino-1,3,4-thiadiazole-2-thiol with nickel(II) and copper(II) metal ions: synthesis, spectroscopic characterization, molecular modeling and fungicidal study.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2014
Same author

Epigenetic regulation of human cytomegalovirus latency: an update.

Epigenomics·2014
Same author

Differential temporal expression of milk miRNA during the lactation cycle of the marsupial tammar wallaby (Macropus eugenii).

BMC genomics·2014
Same author

Association between Functional Severity and Amputation Type with Rehabilitation Outcomes in Patients with Lower Limb Amputation.

Rehabilitation research and practice·2014
Same author

Oxidative nanopeeling chemistry-based synthesis and photodynamic and photothermal therapeutic applications of plasmonic core-petal nanostructures.

Journal of the American Chemical Society·2014

Related Experiment Video

Updated: Jun 18, 2025

Generation of Human Kidney Tubuloids from Tissue and Urine
08:34

Generation of Human Kidney Tubuloids from Tissue and Urine

Published on: April 16, 2021

4.7K

Tubulocystic enteric duplication: a unique entity.

Shreyas Dudhani1, Rashi Rashi2, Amit Kumar Sinha2

  • 1Pediatric Surgery, All India Institute of Medical Sciences, Patna, India shreyas.dudhani45@gmail.com.

BMJ Case Reports
|August 3, 2024
PubMed
Summary

This case report details a rare instance of intestinal duplication cyst in an infant, presenting as a large flank mass. The condition was associated with midgut malrotation and volvulus, highlighting a potential new variant of enteric duplication.

Keywords:
Congenital disordersPaediatric SurgeryPediatricsSmall intestine

More Related Videos

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection
06:05

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Published on: October 12, 2017

15.7K
Establishment of Human Epithelial Enteroids and Colonoids from Whole Tissue and Biopsy
06:33

Establishment of Human Epithelial Enteroids and Colonoids from Whole Tissue and Biopsy

Published on: March 6, 2015

34.8K

Related Experiment Videos

Last Updated: Jun 18, 2025

Generation of Human Kidney Tubuloids from Tissue and Urine
08:34

Generation of Human Kidney Tubuloids from Tissue and Urine

Published on: April 16, 2021

4.7K
Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection
06:05

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Published on: October 12, 2017

15.7K
Establishment of Human Epithelial Enteroids and Colonoids from Whole Tissue and Biopsy
06:33

Establishment of Human Epithelial Enteroids and Colonoids from Whole Tissue and Biopsy

Published on: March 6, 2015

34.8K

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Developmental Biology

Background:

  • Enteric duplication cysts are congenital anomalies with cystic and tubular forms.
  • These malformations can occur anywhere along the gastrointestinal tract.
  • Associated anomalies, such as intestinal malrotation, are documented but uncommon.

Observation:

  • A male infant presented with a large, well-demarcated cystic mass in the right flank.
  • Exploratory laparotomy revealed multiple cystic and tubular lesions near the small bowel's mesenteric border.
  • The infant also exhibited malrotation of the small bowel.

Findings:

  • Histopathological evaluation confirmed an intestinal duplication cyst.
  • The co-occurrence of a large duplication cyst with midgut malrotation and volvulus was noted.
  • The substantial cyst size may have contributed to the malrotation and volvulus.

Implications:

  • This case presents a potential new variant of enteric duplication cysts.
  • Understanding the relationship between cyst size and associated malformations is crucial.
  • The successful surgical management and adaptation of the small bowel offer valuable clinical insights.