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Gastric and sacral electrical stimulation for motility disorders-A clinical perspective
Charlotte Desprez1, Anne-Marie Leroi1, Guillaume Gourcerol1
1Digestive Physiology Department, Rouen University Hospital, Rouen, France.
Background:
Electrical stimulation of the gut has been investigated in recent decades with a view to treating various gastro-intestinal motility disorders including, among others, gastric electrical stimulation to relieve nausea and vomiting associated with gastroparesis and sacral neuromodulation to treat fecal incontinence and/or constipation. Although their symptomatic efficacy has been ascertained by randomized controlled trials, their mechanisms of action are not fully understood.
Purpose:
This review summarizes the past year's literature on the mechanisms of action of gut electrical stimulation therapies, including their impact on the gut-brain axis.
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