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An Approach to Successful Development of Clinician-Scientists in Neurology: The NINDS R25 Experience
S Andrew Josephson1, Michael S Tennekoon2, S Thomas Carmichael3
1Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California, USA.
Annals of Neurology
|August 5, 2024
Summary
The National Institute of Neurologic Disorders and Stroke (NINDS) R25 program successfully supports aspiring clinician-scientists in neurology, increasing K award success rates and reducing time to funding. Academic department support is also crucial for this career path.
Area of Science:
- Neurology
- Medical Education
- Clinical Research
Background:
- Academic neurology departments train clinician-scientists crucial for research.
- Training clinician-scientists faces significant challenges.
- The NINDS R25 program aims to support these trainees and accelerate their careers.
Purpose of the Study:
- To describe the structure and features of the NINDS R25 program.
- To examine the outcomes of the R25 program for neurology trainees.
- To assess the program's impact on K award acquisition and career progression.
Main Methods:
- Review of R25 outcome data from 2009 to 2024.
- Statistical comparisons using Mann-Whitney U testing.
- Analysis of K award application success rates and time to funding.
Main Results:
- R25 support significantly increased K award success for adult (67% vs. 45%) and child neurologists (73% vs. 45%).
- R25 participants achieved K awards faster: 26 months sooner for MD/PhDs and 32 months sooner for MDs.
- The program demonstrated a positive impact on trainee career development.
Conclusions:
- The R25 program is effective in supporting neurology clinician-scientist training.
- The program contributes to successful K award applications and faster career progression.
- Institutional commitment from academic neurology departments is vital for maximizing R25 program success.
