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Related Concept Videos

Transgenic Plants02:50

Transgenic Plants

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Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
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Related Experiment Video

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A Rapid and Efficient Method for Assessing Pathogenicity of Ustilago maydis on Maize and Teosinte Lines
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Assessment of genetically modified maize DP910521 (application GMFF-2021-2473).

, Ewen Mullins, Jean-Louis Bresson

    EFSA Journal. European Food Safety Authority
    |August 5, 2024
    PubMed
    Summary

    Genetically modified maize DP910521, engineered for insect resistance and herbicide tolerance, is as safe as conventional maize for food, feed, and the environment. Molecular and compositional analyses found no safety concerns, including for the novel proteins.

    Keywords:
    Cry1B.34DP910521GMPATPMIgenetic engineeringimport and processingmaize (Zea mays)

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    Area of Science:

    • Agricultural Science
    • Biotechnology
    • Food Safety

    Background:

    • Genetically modified (GM) maize DP910521 was developed using expression cassettes for insect resistance and herbicide tolerance.
    • Key genes introduced include mo-pat, pmi, and cry1B.34.

    Purpose of the Study:

    • To assess the food, feed, and environmental safety of GM maize DP910521.
    • To compare the safety profile of GM maize DP910521 with its conventional counterpart.

    Main Methods:

    • Molecular characterization and bioinformatic analyses.
    • Agronomic, phenotypic, and compositional analyses.
    • Toxicity and allergenicity assessment of introduced proteins (Cry1B.34, PAT, PMI).

    Main Results:

    • No safety concerns identified in molecular and bioinformatic analyses.
    • Iron levels in grain were the only difference noted, posing no safety or nutritional issues.
    • The introduced proteins (Cry1B.34, PAT, PMI) were found to be non-toxic and non-allergenic.
    • No adverse effects on human or animal health or the environment were detected.

    Conclusions:

    • GM maize DP910521 is as safe as conventional maize varieties for consumption and environmental release.
    • No post-market monitoring for food, feed, or the environment is deemed necessary.
    • The genetic modification does not impact the overall safety of maize DP910521.