Advancing research on Blastocystis through a One Health approach

Area of Science:

• Microbiology
• One Health
• Parasitology

Background:

• Blastocystis is the most common intestinal eukaryotic microorganism, affecting both human and animal health.
• Its role in disease (pathogenicity) remains controversial despite extensive research.
• A multidisciplinary approach is needed to address knowledge gaps.

Purpose of the Study:

• To establish a unified network for Blastocystis research under the One Health framework.
• To develop standardized diagnostic methods and create a comprehensive subtype and microbiome database.
• To promote capacity building through education and collaboration in Blastocystis research.

Main Methods:

• Formation of a COST Action (CA21105) involving a multidisciplinary network.
• Structuring the initiative into five working groups focusing on epidemiology, diagnostics, 'omics, in vivo/in vitro studies, and data dissemination.
• Integrating knowledge from medical, veterinary, public, and environmental health sectors.

Main Results:

• Development of standardized diagnostic methodologies is a key focus.
• Establishment of a comprehensive databank for Blastocystis subtypes and associated microbiomes.
• Promotion of capacity building via education and collaborative research efforts.

Conclusions:

• The OneHealthBlastocystis initiative aims to harmonize diagnostics and improve public health policies.
• This collaborative effort will enhance understanding of Blastocystis' role in health and disease.
• Expected outcomes include significant advancements and practical applications benefiting scientific and public health communities.