C-reactive protein point-of-care testing in primary care-broader implementation needed to combat antimicrobial...

Area of Science:

• Infectious Diseases
• Public Health
• Clinical Diagnostics

Background:

• Antimicrobial resistance (AMR) is a global health crisis, driven by overuse of antibiotics, particularly for respiratory tract infections (RTIs) in primary care.
• C-reactive protein point-of-care testing (CRP POCT) is a proven, cost-effective tool to guide antibiotic prescribing for RTIs.
• Despite evidence, CRP POCT implementation for antibiotic stewardship remains inconsistent across many European countries.

Purpose of the Study:

• To provide expert guidance for the sustainable implementation of CRP POCT in primary care.
• To support informed antibiotic prescribing decisions for RTIs and mitigate AMR.
• To outline necessary policy and practice changes for effective CRP POCT integration.

Main Methods:

• Review of existing models and policies for CRP POCT implementation.
• Expert consensus on strategies for sustainable adoption and optimal use.
• Identification of complementary interventions to support antibiotic stewardship.

Main Results:

• CRP POCT can safely and effectively reduce antibiotic prescribing for RTIs.
• Successful implementation requires a multifaceted approach including clear guidelines, physician training, and supportive policies.
• Integration into professional guidelines, adequate reimbursement, and accessible POCT organization are crucial.

Conclusions:

• CRP POCT is a valuable tool in the fight against AMR when implemented strategically.
• Sustainable use necessitates a combination of technological support, professional education, and policy changes.
• Collaborative efforts among all stakeholders are essential for maximizing the impact of CRP POCT in primary care.