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Related Experiment Video

Updated: Jun 18, 2025

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
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Pain in Multiple System Atrophy: A Community-Based Survey.

Nicole Campese1, Georg Göbel2, Julia Wanschitz1

  • 1Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Movement Disorders : Official Journal of the Movement Disorder Society
|August 5, 2024
PubMed
Summary

Pain significantly impacts individuals with Multiple System Atrophy (MSA), affecting 87% of patients, particularly women and low-income groups. Current pain management is suboptimal, indicating a need for improved therapeutic strategies.

Keywords:
multiple system atrophynon‐motor symptomspainquality of life

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Area of Science:

  • Neurology
  • Pain Medicine
  • Clinical Research

Background:

  • Multiple System Atrophy (MSA) is frequently associated with pain, a poorly understood symptom.
  • Effective pain management is crucial for improving the quality of life in MSA patients.

Purpose of the Study:

  • To assess the prevalence and characteristics of pain in Multiple System Atrophy (MSA).
  • To evaluate current pain treatment strategies and patient satisfaction in MSA.

Main Methods:

  • An online survey was conducted from February to May 2023, including 190 persons with MSA and 114 caregivers.
  • Data collection involved patient advocacies and social media outreach.

Main Results:

  • Pain was reported by 87% of MSA individuals, with higher prevalence in women and low-income groups.
  • Neck, shoulders, back, and legs were commonly affected areas. Pain correlated with MSA features like orthostatic intolerance and antecollis.
  • While 76% received treatment (NSAIDs, acetaminophen, opioids), only 53% reported partial satisfaction.

Conclusions:

  • Pain is highly prevalent in MSA, disproportionately affecting women and low-income individuals.
  • Current pain management in MSA is suboptimal, necessitating improved therapeutic approaches.
  • Optimizing the management of core motor and non-motor features of MSA may help alleviate pain.