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Published on: October 12, 2017
Diagnostic Accuracy of Ureteric Jet Angle Measurement Using Color Doppler Ultrasonography in Children With
Cameron Gemmell1, Christopher Edwards2,3, Tristan Reddan2,4
1University of Queensland, St Lucia, Queensland, Australia.
Insights
Color Doppler sonography
Area of Science:
- Pediatric nephrology
- Diagnostic imaging
- Urology
Background:
- Vesico-ureteric reflux (VUR) is a common condition in children.
- Accurate diagnosis of VUR is crucial for appropriate management and prevention of renal scarring.
- Current diagnostic methods have limitations, necessitating exploration of alternative techniques.
Approach:
- A systematic review was conducted to evaluate the diagnostic accuracy of ureteric jet angles using color Doppler sonography for VUR in children.
- Six databases were searched, identifying 13 eligible studies.
- The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool was used to assess the risk of bias and applicability of the included studies.
Key Points:
- Most studies indicated a correlation between increasing ureteric jet angle and VUR severity.
- Significant variations in reporting and sonographic techniques were observed across studies.
- These variations precluded a meta-analysis of the data.
Conclusions:
- Ureteric jet angle sonography shows potential as a non-invasive VUR triaging tool in pediatric patients.
- Further high-quality research with standardized methodologies is essential to confirm its diagnostic utility.
- Robust investigations are needed to establish definitive guidelines for its use in clinical practice.
Abstract:
This systematic review evaluated accuracy of ureteric jet angles on color Doppler sonography in diagnosing vesico-ureteric reflux (VUR) in children, using voiding cystourethrogram as the reference standard. Six databases were searched, yielding 13 eligible studies of an initial 429, 7 with comparable data. Risk of bias and applicability were assessed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool. Most studies demonstrated a correlation between increasing jet angle and VUR severity, but reporting and techniques varied, preventing meta-analysis. Ureteric jet angle sonography may have potential as a VUR triaging tool. Further investigations with rigorous methodology are required. Funding support was obtained from Queensland University of Technology. PROSPERO Registration CRD42020159799.
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Imaging Studies I: Kidney, Ureter, and Bladder Studies
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Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Imaging Studies VI: Voiding Cystourethrography and Cystography
Urodynamic Studies: Uroflowmetry
Urologic Endoscopic Procedure: Cystoscopic Examination

