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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

Knowledge-based representation: Patient engagement in drug development.

Claudia Egher¹, Olga Zvonareva²

¹Innovation Studies, Copernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.

Health Expectations : an International Journal of Public Participation in Health Care and Health Policy

|August 5, 2024

Summary

This summary is machine-generated.

Patient representation in drug development is evolving, emphasizing knowledge-based representation. This involves drug development, autobiographical, and community knowledge for effective patient advocacy.

Keywords:

drug development knowledge knowledge‐based representation participation patient engagement representation

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Area of Science:

Health Sciences
Social Sciences

Background:

Growing emphasis on patient involvement in drug development.
Need to understand the configuration of patient representation.

Purpose of the Study:

Investigate how patient representation is configured in drug development.
Identify the roles and expectations of patient representatives.

Main Methods:

Qualitative study using thematic analysis.
40 semistructured interviews with stakeholders.
Analysis of patient engagement guides and forum observations.

Main Results:

Patient representation relies on drug development, autobiographical, and community knowledge.
A new model termed 'knowledge-based representation' is identified.
This model better describes how patients represent others.

Conclusions:

Knowledge-based representation highlights epistemic elements over political ones.
The democratic impact depends on resources and knowledge determination.
Political aspects of patient representation remain crucial.