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Neuroprognostication after cardiac arrest: Don't forget the good!

Pascal Stammet1

  • 1Department of Anaesthesia and Intensive Care Medicine, Centre Hospitalier de Luxembourg, 4, rue Barblé, L-1210 Luxembourg, Luxembourg; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine, University of Luxembourg, 2, place de l'Université, L-4365 Esch-sur-Alzette, Luxembourg.

Resuscitation
|August 5, 2024
PubMed
Summary

No abstract available in PubMed .

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Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
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