Locomotion and chemotaxis of mononuclear phagocytes

The capacity for locomotion and for chemotaxis is probably very different in monocytes and macrophages from different sources. Numerous techniques have been established for studying the locomotion of these cells. Many of the factors are sparsely documented and the reports are scattered among various cell types. Heterogeneity of locomotion and chemotactic responsiveness is evident when established macrophage lines and mouse peritoneal macrophage are studied. The effects of mononuclear phagocytes and their released products on the locomotion of other cell types are reviewed.