Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The contaminated small bowel syndrome.

P E Isaacs, Y S Kim

    The American Journal of Medicine
    |December 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Small intestinal bacterial overgrowth disrupts digestion and nutrient absorption. Antibacterial therapy can reverse these malabsorption issues, confirming the diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Malignant hepatic tumours associated with previous exposure to Thorotrast: four cases.

    European journal of gastroenterology & hepatology·1996
    Same author

    Cloning and characterization of rat pancreatic beta-cell/liver type glucose transporter gene: a unique exon/intron organization.

    Archives of biochemistry and biophysics·1995
    Same author

    Regional expression and dietary regulation of rat small intestinal peptide and amino acid transporter mRNAs.

    Biochemical and biophysical research communications·1995
    Same author

    Human dipeptidyl peptidase IV gene promoter: tissue-specific regulation from a TATA-less GC-rich sequence characteristic of a housekeeping gene promoter.

    The Biochemical journal·1995
    Same author

    Linear IgA dermatosis, coeliac disease, and extraintestinal B cell lymphoma.

    Gut·1995
    Same author

    Genomic aberrations in human hepatoblastomas detected by 2-dimensional gel analysis.

    Cancer research·1995

    Area of Science:

    • Gastroenterology
    • Microbiology

    Background:

    • Small intestinal bacterial overgrowth (SIBO) involves an abnormal microflora in the small bowel.
    • This overgrowth leads to impaired intraluminal digestion and mucosal function.
    • Consequences include malabsorption of essential nutrients like fats, proteins, carbohydrates, electrolytes, and vitamin B12.

    Purpose of the Study:

    • To highlight the diagnostic challenges and therapeutic confirmation of small intestinal bacterial overgrowth.
    • To emphasize the role of diagnostic methods in establishing a pretreatment diagnosis.

    Main Methods:

    • Utilizing indirect clinical tests for SIBO.
    • Supplementing clinical tests with roentgenologic examination of the small intestine.
    • Performing intestinal aspiration studies for definitive diagnosis.

    Related Experiment Videos

    Main Results:

    • SIBO causes significant malabsorption of various nutrients and vitamins.
    • Diagnostic confirmation requires a combination of clinical, radiological, and microbiological assessments.
    • Reversal of absorptive defects following antibacterial therapy serves as crucial confirmatory evidence.

    Conclusions:

    • A firm pretreatment diagnosis of SIBO is essential for effective management.
    • Antibacterial therapy is a key treatment modality.
    • The response to therapy validates the diagnosis and indicates successful management of malabsorption.