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Unlocking hypoglycemia-associated brain microvascular dysfunction: critical insights from proteomic analysis

Siva S V P Sakamuri1, Anil Sakamuri2

  • 1Department of Chemistry, Auburn University at Montgomery, Montgomery, AL, USA (Sakamuri SSVP).

Neural Regeneration Research
|August 6, 2024
PubMed
Abstract

No abstract available in PubMed .

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Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
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