Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Infertility in Males01:23

Infertility in Males

256
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
256
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

370
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
370
Testes: Histology01:27

Testes: Histology

779
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
779

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of miR-155 and IL-6 in the shared pathogenesis of periodontitis and rheumatoid arthritis: a cross-sectional case-control study.

Journal of periodontal & implant science·2026
Same author

Re-Imagining Male Infertility Guidelines Through the Global Andrology Forum.

The world journal of men's health·2026
Same author

Closing the Gap in Erectile Dysfunction Evaluation: Practical Insights for the Frontline Urologist.

The world journal of men's health·2026
Same author

Impact of Intraoperative Doppler Ultrasound on Outcomes of Microsurgical Subinguinal Varicocelectomy: A Systematic Review and Meta-Analysis.

The world journal of men's health·2026
Same author

Non-Pharmacological Therapies for Erectile Dysfunction: What is New, What Works, What is Next.

The world journal of men's health·2026
Same author

Management of Non-Obstructive Azoospermia: Practical Answers to Key Clinical Questions.

The world journal of men's health·2026
Same journal

Molecular mechanisms of erectile dysfunction in type 1 and type 2 diabetic rats: a multiomics approach.

Asian journal of andrology·2026
Same journal

The long (GGN)n repeat tract in the androgen receptor gene exerts a negative effect on quantitative sperm parameters.

Asian journal of andrology·2026
Same journal

Exploring potential targets and mechanisms of male reproductive toxicity induced by the emerging PFAS GenX and F-53B via network toxicology, molecular docking, and in vivo validation.

Asian journal of andrology·2026
Same journal

Modifiable key factors and semen quality in men undergoing preconception evaluation: a cross-sectional study.

Asian journal of andrology·2026
Same journal

Somatic cell reprogramming into stem cells: approaches, mechanisms, and therapeutic applications.

Asian journal of andrology·2026
Same journal

A homozygous splicing mutation in CCDC39 caused multiple morphological abnormalities of the flagella in an infertile man with primary ciliary dyskinesia.

Asian journal of andrology·2026
See all related articles

Related Experiment Video

Updated: Jun 17, 2025

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
06:28

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Published on: May 27, 2022

3.7K

Varicocele and nonobstructive azoospermia.

Parviz K Kavoussi1, Chirag Gupta2, Rupin Shah3,4

  • 1Department of Reproductive Urology, Austin Fertility and Reproductive Medicine/Westlake IVF, Austin, TX 78746, USA.

Asian Journal of Andrology
|August 6, 2024
PubMed
Summary
This summary is machine-generated.

Varicoceles affect male fertility and azoospermia. Varicocele repair may improve semen parameters and sperm retrieval success in men with non-obstructive azoospermia.

Keywords:
azoospermiainfertilityvaricocele

More Related Videos

Clinical Application of 24 G Cannula Needle and 3-0 Polypropylene Suture in Vas Deferens Exploration
07:21

Clinical Application of 24 G Cannula Needle and 3-0 Polypropylene Suture in Vas Deferens Exploration

Published on: February 10, 2023

2.6K
Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
04:15

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach

Published on: November 22, 2024

128

Related Experiment Videos

Last Updated: Jun 17, 2025

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
06:28

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Published on: May 27, 2022

3.7K
Clinical Application of 24 G Cannula Needle and 3-0 Polypropylene Suture in Vas Deferens Exploration
07:21

Clinical Application of 24 G Cannula Needle and 3-0 Polypropylene Suture in Vas Deferens Exploration

Published on: February 10, 2023

2.6K
Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
04:15

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach

Published on: November 22, 2024

128

Area of Science:

  • Reproductive Medicine
  • Andrology
  • Urology

Background:

  • Varicoceles are common, affecting 15% of men generally and 40% of those with fertility issues.
  • Azoospermia (lack of sperm in ejaculate) affects 1% of men generally and 15% of those with fertility issues.

Purpose of the Study:

  • To review the impact of varicoceles on testicular function in azoospermic men.
  • To assess varicocele repair's effect on semen parameters in azoospermic men.
  • To evaluate varicocele repair's impact on sperm retrieval and pregnancy outcomes in persistent azoospermia.

Main Methods:

  • Literature review of studies on varicoceles and azoospermia.
  • Analysis of data on testicular function, semen parameters, and reproductive outcomes post-repair.

Main Results:

  • Varicoceles negatively impact testicular function in azoospermic men.
  • Varicocele repair can improve semen parameters in some azoospermic men.
  • Repair may enhance sperm retrieval rates and pregnancy success in persistent azoospermia.

Conclusions:

  • Varicocele diagnosis and management are crucial in male fertility evaluations.
  • Varicocele repair is a potential therapeutic option for selected azoospermic men.
  • Further research is needed on optimizing outcomes for persistent azoospermia post-repair.