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"Under the hood": artificial intelligence in personalized radiotherapy.

Chiara Gianoli1, Elisabetta De Bernardi2, Katia Parodi1

  • 1Department of Experimental Physics - Medical Physics, Faculty for Physics of the Ludwig-Maximilians-Universität München (LMU Munich), Geschwister-Scholl-Platz 1, München, 80539, Germany.

BJR Open
|August 6, 2024
PubMed
Summary

Artificial intelligence (AI) enhances radiotherapy by streamlining anatomy-based workflows and enabling biology-driven treatments through radiomics and dosiomics. AI is crucial for advancing personalized radiation therapy.

Keywords:
adaptive radiation therapyartificial intelligencedeep learningmachine learningpersonalized radiation treatmentradiotherapy

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Area of Science:

  • Radiotherapy
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Radiotherapy workflow involves complex tasks, with potential for enhancement through AI.
  • Personalized treatments are evolving, moving from anatomy-based to biology-driven approaches.

Purpose of the Study:

  • To review the current and future applications of artificial intelligence (AI) in radiotherapy.
  • To explore AI's role in both anatomy-based and biology-driven radiotherapy workflows.
  • To highlight AI methodologies like radiomics, dosiomics, and multiomics for personalized treatments.

Main Methods:

  • Review of existing literature on AI in radiotherapy.
  • Categorization of AI applications based on anatomy-based (adaptive) and biology-driven workflows.
  • Discussion of AI tools for radiomics, dosiomics, and multiomics.

Main Results:

  • AI streamlines anatomy-based radiotherapy, reducing time and variability.
  • AI is essential for biology-driven workflows, enabling advanced decision-making.
  • AI methodologies like radiomics and dosiomics are key to personalized radiation treatments.

Conclusions:

  • AI is increasingly vital for personalized radiotherapy.
  • AI offers significant potential to improve efficiency and outcomes in radiation therapy.
  • Future research and clinical integration of AI in radiotherapy are expanding.