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5' Transgenes drive leaky expression of 3' transgenes in Cre-inducible bi-cistronic vectors

Yasuyuki Osanai1,2, Yao Lulu Xing1, Shinya Mochizuki3

  • 1Australian Regenerative Medicine Institute, Monash University, 15 Innovation Walk, Clayton, VIC 3800, Australia.

Molecular Therapy. Methods & Clinical Development
|August 6, 2024
PubMed

Keywords:
AAVDIOFLExbi-cistronic vectorgene expressionleak expressionlox-STOP-loxpoly-cistronic vector

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