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Updated: Jun 17, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Pseudoprogression of cutaneous squamous cell carcinoma invading the super vermillion border following programmed
Sach Thakker1, Naghmeh Yousefzadeh2, Jafar Al-Mondhiry3,4
1Georgetown University School of Medicine Washington District of Columbia USA.
Abstract:
A 55-year-old woman with a moderately differentiated cutaneous squamous cell carcinoma (cSCC) of the upper lip experienced initial tumour growth and new lymphadenopathy after starting immunotherapy with Cemiplimab, but achieved complete remission with no adverse events after five infusions. This case underscores the potential of immunotherapy for cSCC in sensitive head and neck areas and illustrates the phenomenon of pseudoprogression, where apparent tumour growth can occur before clinical improvement.
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