Related Experiment Video
Updated: Jun 17, 2025

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Condition of oral tissues in children with congenital cleft lip and palate
1BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE; NATIONAL SPECIALIZED CHILDREN'S HOSPITAL "OKHMATDYT", KYIV, UKRAINE.
Insights
Children with congenital complete cleft lip and palate exhibit high rates of dental anomalies like adentia and retention, alongside prevalent oral diseases. These conditions significantly complicate surgical and orthodontic rehabilitation efforts.
Area of Science:
- Pediatric Dentistry
- Oral and Maxillofacial Surgery
- Congenital Anomalies
Background:
- Congenital complete cleft lip, alveolar process, hard, and soft palate are complex conditions affecting oral tissue development.
- Understanding the oral health status in these children is crucial for effective treatment planning.
Purpose of the Study:
- To investigate the prevalence of dental anomalies and oral diseases in children with congenital complete cleft lip and palate.
- To assess the impact of these conditions on oral health and rehabilitation outcomes.
Main Methods:
- Clinical and radiological analysis of 302 children (aged 8-18) with unilateral or bilateral complete cleft lip and palate.
- Evaluation of primary dentition, dental anomalies (adentia, retention, supernumerary teeth), caries, periodontal status, and soft tissue conditions.
Main Results:
- High prevalence of adentia (69.53%), retention, and supernumerary teeth, with variations between sexes and cleft types.
- Over 90% of patients had caries; 80.75% showed periodontal inflammation.
- Significant occurrences of cheilitis and glossitis were observed.
Conclusions:
- Congenital complete cleft lip and palate are associated with substantial dental anomalies and oral pathologies.
- These oral health issues present significant challenges for successful surgical and orthodontic rehabilitation.
Objective:
Aim: To study the condition of oral tissues in children with congenital complete cleft lip, alveolar process, hard and soft palate.
Patients And Methods:
Materials and Methods: From the examined 470 children National Specialized Children's Hospital "OKHMATDYT" (Kyiv, Ukraine) with congenital cleft lip and palate was analyzed: 302 patients aged 8-18 years were subject to in-depth analysis for clinical and radiological - 192 with unilateral and 110 with bilateral complete cleft lip, alveolar process, hard and soft palate.
Results:
Results: The average value of primary adention in patients with unilateral and bilateral complete combined cleft is 69.53%, but in females this indicator is higher and in unilateral cleft 92.18% for female against 53.17% for male. In females with unilateral cleft retention - 40.62% and overcomplete - 10,93%. The same high indicators in bilateral cleft: retention - 36.58% and overcomplete - 12.19%. Retention and overcomplete have higher values for men - 44.93% and 23.19%, respectively. Chewing efficiency in females with bilateral cleft as a result of primary dentition is below 80%. Affected by caries - 90.73% in both groups. Inflammatory processes in the periodontal tissues are revealed (80,75%): chronic catarrhal gingivitis, chronic hypertrophic gingivitis, chronic generalized periodontitis. Manifestations of atopic and angular cheilitis in 39.09% and 23.63% with bilateral cleft lip and palate, glossitis in 29.09%.
Conclusion:
Conclusions: Patients with congenital complete cleft lip, alveolar process, hard and soft palate have high rates of adentia, retention, overcomplete dentition and a wide range of diseases of the oral cavity, which negatively affects surgical and orthodontic rehabilitation.
Related Concept Videos
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Oral Cavity
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Psychosexual Stages of Personality: Oral
Weaning, typically occurring...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...

