Related Experiment Video
Updated: Jun 17, 2025

07:40
A Noninvasive Hair Sampling Technique to Obtain High Quality DNA from Elusive Small Mammals
Published on: March 13, 2011
20.8K
Rogue Hairs: A Mixed-Method Characterization of a Previously Unreported Entity
Anise Marshall1, Andrea Kalus2, April Schachtel2
1University of Washington School of Medicine, University of Washington, Seattle, WA, USA.
Skin Appendage Disorders
|August 7, 2024
Summary
Rogue hairs, unusually long facial hairs, are a common yet undocumented phenomenon affecting 18% of surveyed patients. This study defines rogue hairs and explores their prevalence and patient experiences.
Area of Science:
- Dermatology
- Clinical Phenotyping
- Patient-Reported Outcomes
Background:
- Rogue hairs, defined as unusually long facial hairs outside typical areas, represent a common, previously undocumented phenomenon.
- Understanding the prevalence and characteristics of rogue hairs is essential for addressing patient concerns.
Purpose of the Study:
- To define rogue hairs on the face.
- To describe the frequency and clinical features of rogue hairs.
- To investigate patient experiences with rogue hairs.
Main Methods:
- A mixed-method approach combining a case series, patient surveys, and social media analysis.
- Dermatologist identification of clinical cases and qualitative thematic analysis of social media comments.
- Administration of surveys to patients at an academic dermatology clinic.
Main Results:
- Rogue hairs were observed in children and adults across all races and genders.
- 18% of surveyed patients reported experiencing rogue hairs.
- Social media analysis revealed common themes of sudden appearance, frequent removal, and infrequent dermatological consultation.
Conclusions:
- Rogue hairs are a prevalent, benign facial hair phenomenon.
- Social media can serve as a valuable tool for clinical inquiry and understanding patient experiences.
- Further research is needed to elucidate the biological mechanisms underlying rogue hairs.
Related Concept Videos
Multipotency and Niche of Bulge Stem Cell
3.5K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
3.5K
Epistasis
46.6K
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
46.6K
Pleiotropy
40.3K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
40.3K

