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Choroiditis following severe acute respiratory syndrome coronavirus 2 infection in unvaccinated identical twins
Luiz Guilherme Marchesi Mello1,2,3, Lara Guedes Lubiana2, Carlos Eduardo Hirata1
1Division of Ophthalmology and Laboratory of Investigation in Ophthalmology (LIM-33), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Abstract:
Unvaccinated identical twins developed bilateral anterior uveitis soon after the onset of coronavirus disease 2019 symptoms. During follow-up, both patients developed choroiditis, and one twine developed posterior scleritis and serous retinal detachment. Prompt treatment with oral prednisone ameliorated the lesions, and no recurrence was observed at the 18-month follow-up. Choroiditis may rarely be associated with severe acute respiratory syndrome coronavirus 2 infection, and it responds well to corticosteroid therapy. Although the exact mechanism is unknown, we hypothesize that the virus may act as an immunological trigger for choroiditis.
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