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Feedback Inhibition

Feedback Inhibition

Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!

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Related Experiment Video

Updated: Jun 22, 2026

Force and Position Control in Humans - The Role of Augmented Feedback

Force and Position Control in Humans - The Role of Augmented Feedback

Published on: June 19, 2016

Task-relevant visual feedback uncertainty attenuates visuomotor adaptation.

Virginia Casasnovas^1,2, Lukas K Amann^1,2, Gianna L Haas²

¹Sensorimotor Group, German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.

Journal of Neurophysiology

|August 7, 2024

Summary

This summary is machine-generated.

Motor adaptation learning is reduced when task-relevant visual feedback is uncertain. This suggests the motor system adjusts learning based on feedback reliability, even with large errors.

Keywords:

motor adaptation task-relevant error visual feedback uncertainty

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Area of Science:

Neuroscience
Motor Control
Human Movement Science

Background:

Motor adaptation typically decreases with uncertain sensory feedback.
Previous studies suggested this attenuation might not apply to large visual errors when feedback is task-irrelevant.
The role of uncertainty in task-relevant feedback for large errors remained unclear.

Purpose of the Study:

To investigate if motor adaptation to large perturbations is attenuated by uncertainty in task-relevant visual feedback.
To determine the impact of visual feedback uncertainty on both implicit and explicit adaptation processes.

Main Methods:

Participants performed a visuomotor rotation task with varying levels of visual feedback uncertainty (low vs. high).
The error-clamp method was used in a second experiment to isolate implicit adaptation.
Implicit and explicit adaptation contributions were quantified across different feedback conditions.

Main Results:

High visual feedback uncertainty significantly reduced both the initial and final extent of motor adaptation.
Implicit adaptation was consistently smaller under high feedback uncertainty compared to low uncertainty.
Explicit adaptation contributions were minimal, especially under high uncertainty.

Conclusions:

Task-relevant visual feedback uncertainty influences implicit motor adaptation, even for large errors.
The motor system is sensitive to feedback reliability and adjusts learning rates accordingly.
Adaptation depends on the assessment of both sensory prediction errors and target errors.