[Tubular involvement during non-oliguric rhabdomyolysis. (Apropos of 2 cases)]

The authors report two cases of severe rhabdomyolysis in a 23-year-old woman following a toxic coma with muscular compression and in a 34-year-old man after a febrile state. Despite clinical and biological signs of marked muscular necrosis, oliguric acute renal failure did not occur. However, repetitive urinary dosage of N-acetyl-glucosaminidase (NAG), of retinol-binding-protein (RBP) and of beta-2-microglobulin (beta-2-m) revealed an early and long-standing tubular dysfunction not suggested by conventional laboratory data.