Related Experiment Video
Updated: Jun 30, 2026
07:57
Methods for Acute and Subacute Murine Hindlimb Ischemia
Published on: June 21, 2016
16.3K
Surgical Interventions for Acute Limb Ischaemia (ALI)
Zia Ur Rehman1, Faisal Sher1, Mohammad Hamza Bajwa1
1Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan.
Summary
Acute limb ischaemia (ALI) often presents as Rutherford Class II, primarily caused by thromboembolism. Embolectomy is the common intervention, but carries significant amputation and mortality risks.
Area of Science:
- Vascular Surgery
- Clinical Medicine
- Public Health
Background:
- Acute limb ischaemia (ALI) is a critical condition requiring prompt management.
- Understanding the presentations, causes, treatments, and outcomes of ALI is vital for improving patient care.
- Key factors include thromboembolism, comorbidities like hypertension and diabetes, and surgical interventions such as embolectomy.
Purpose of the Study:
- To comprehensively evaluate the clinical presentations, underlying aetiologies, interventions performed, and patient outcomes in acute limb ischaemia.
- To analyze demographic characteristics, common comorbidities, and diagnostic findings in patients with ALI.
- To assess the effectiveness and associated risks of surgical interventions for ALI.
Main Methods:
- An observational study was conducted retrospectively on 104 patients who underwent surgical interventions for ALI.
- Diagnosis was confirmed using imaging modalities including ultrasound, CTA, and conventional angiography.
- Data on demographics, comorbidities, aetiologies, interventions, and outcomes were analyzed using descriptive statistics and logistic regression.
Main Results:
- The study cohort had a mean age of 58.89 years, with a slight female predominance (54.8%).
- Common comorbidities included hypertension (54.8%), diabetes (46.2%), and atrial fibrillation (34.6%).
- Thromboembolism (67.3%) was the leading aetiology, predominantly affecting the lower limb and femoral artery. Most patients presented with Rutherford classification 2A or 2B. Embolectomy was the most frequent intervention (80.8%), associated with a 17.3% amputation rate and a 5.8% mortality rate.
Conclusions:
- Patients with ALI frequently present with Rutherford Class II and have a thromboembolic aetiology.
- Embolectomy remains the primary surgical intervention for ALI.
- The procedure is associated with notable rates of amputation and mortality, highlighting the need for optimized management strategies.
Related Concept Videos
01:26Flail Chest-II
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Assessment:
1. Clinical Evaluation:
History:
01:28Acute Coronary Syndrome IV: Interprofessional Care
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
01:27Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
01:23Peripheral Artery Disease V: Postoperative Nursing Management
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
01:22Aneurysm IV: Nursing Management
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...